怪物Monster)代表角色在游戏过程中将会遇到的各种敌对生物。

大多数怪物会通过接触或发射眼泪的方式对角色造成伤害(少部分除外)。个别情况下,怪物会不断孵化出更小的怪物、分泌蠕液,或者试图阻碍玩家的移动。Along with the more common variety of monsters, champion versions can be found lurking about. These monsters are often like their common counterparts, but have a color tint or size change and drop basic pickups on death. There are also champion versions of most bosses.

怪物列表

敌人图鉴
第1页 第2页 第3页 第4页
Frowning Gaper.png Gaper.png Flaming Gaper.png Gusher.png Maggot.png Hive.png Drowned Hive.png Charger.png Hopper.png Trite.png Boil.png Gut.png Guts.png Scarred Guts.png Knight.png Selfless Knight.png
Pacer.png Horf.png Fly.png Pooter.png Drowned Charger.png Globin.png Gazing Globin.png Dank Globin.png Sack.png Spitty.png Brain.png Leaper.png Stone Grimace.png Vomit Grimace.png Poky.png Slide.png
Super Pooter.png Clotty.png Clot.png I.Blob.png Boom Fly.png Red Boom Fly.png Drowned Boom Fly.png Maw.png Mr. Maw.png Mr. Maw.png Baby.png Angelic Baby.png Dople.png Evil Twin.png Flaming Hopper.png Leech (Monster).png
Mulligan.png Mulligoon.png Mulliboom.png Attack Fly.png Red Maw.png Psychic Maw.png Host.png Red Host.png Vis.png Double Vis.png Chubber.png Scarred Double Vis.png Kamikaze Leech.png Holy Leech.png Lump.png MemBrain.png
第5页 第6页 第7页 第8页
Mama Guts.png Para-Bite.png Scarred Para-Bite.png Fred.png Buttlicker.png Hanger.png Swarmer.png Heart.png Fatty.png Pale Fatty.png Flaming Fatty.png Fat Sack.png Wall Hugger.png Wizoob.png Squirt.png Dank Squirt.png
Eye.png Bloodshot Eye (Monster).png Sucker.png Spit.png Mask.png Big Spider.png Eternal Fly.png Stone Eye.png Blubber.png Half Sack.png Death's Head.png Dank Death's Head.png Cod Worm.png Ring Fly.png Dinga.png Oob.png
Empryo.png Moter.png Spider.png Keeper.png Turret Grimace.png Brimstone Grimace.png Mobile Host.png Nest.png Mom's Hand.png Level 2 Fly.png Level 2 Spider.png Swinger.png Black Maw.png Skinny.png Rotty.png Bony.png
Gurgle.png Walking Boil.png Walking Gut.png Walking Sack.png Baby Long Legs.png Small Baby Long Legs.png Crazy Long Legs.png Small Crazy Long Legs.png Swinger.png Dip.png Corn Dip.png Corn Dip.png Homunculus.png Tumor.png Camillo Jr..png Nerve Ending.png
第9页 第10页 第11页 第12页
Nerve Ending 2.png One Tooth.png Gaping Maw.png Broken Gaping Maw.png Ticking Spider.png Begotten.png Null.png Psy Tumor.png Swarm Fly.png Mega Clotty.png Bone Knight.png Cyclopia.png Poison Mind.png Stoney.png Blister.png The Thing.png
Gurgling.png Splasher.png Grub.png Wall Creep.png Floating Knight.png Nightcrawler.png Dart Fly.png Conjoined Fatty.png Red Ghost.png Flesh Death's Head.png Mom's Dead Hand.png Dukie.png Ministro.png Portal.png
Rage Creep.png Blind Creep.png Conjoined Spitty.png Round Worm.png Blue Conjoined Fatty.png Fat Bat.png Imp.png Roundy.png Ulcer.png Meatball.png Corn Mine.png Hush Fly.png
Ragling.png Flesh Mobile Host.png Psychic Horf.png Full Fly.png Black Bony.png Black Globin.png Black Globin's Head.png Black Globin's Body.png Blue Gaper.png Blue Boil.png Greed Gaper.png Mushroom (Monster).png
第13页 第14页 第15页 第16页
Larry Jr..png The Hollow.png C.H.A.D..png Carrion Queen.png Monstro II.png Gish.png Super Sloth.png Ultra Pride.png
Monstro.png Chub.png Gurdy.png Ultra Pride Baby.png Mom.png Sloth.png Lust.png Super Lust.png
第17页 第18页 第19页 第20页
Wrath.png Super Wrath.png Greed.png Super Greed.png Pride.png Super Pride.png The Frail.png Famine.png
Gluttony.png Super Gluttony.png Envy.png Super Envy.png Pin.png Scolex.png Pestilence.png War.png
第21页 第22页 第23页 第24页
Conquest.png Death.png Peep.png The Bloat.png Fistula.png Teratoma.png It Lives.png Gemini (Boss).png
The Duke of Flies.png The Husk.png Loki.png Lokii.png Blastocyst.png Mom's Heart.png Steven (Boss).png The Blighted Ovum.png
第25页 第26页 第27页 第28页
Gemini Baby.png Steven Baby.png Krampus.png Headless Horseman.png Mask of Infamy (Mask).png Mask of Infamy (Heart).png The Wretched.png Daddy Long Legs.png
The Blighted Ovum Baby.png The Fallen.png Headless Horseman Head.png Satan.png Gurdy Jr..png Widow.png Triachnid.png Isaac (Boss).png
第29页 第30页 第31页 第32页
Blue Baby (Boss).png Gurgling.png Lil' Haunt (Boss).png Dingle.png The Gate.png Mega Fatty.png Dark One.png The Adversary.png
Turdling.png Haunt.png Dangle.png Mega Maw.png The Cage.png Mama Gurdy.png Polycephalus.png Mr. Fred.png
第33页 第34页 第35页 第36页
Uriel.png Fallen Uriel.png The Lamb.png Mega Satan's Head.png Brownie.png The Forsaken.png Ultra Greed.png Ultra Greedier.png
Gabriel.png Fallen Gabriel.png Mega Satan 2's Head.png The Stain.png Little Horn (Boss).png Rag Man.png Hush.png Rag Mega.png
第37页
Sister Vis.png Big Horn.png
Delirium.png

精英怪物

Ed's basic example of potential color variations.

Some monsters can spawn as a Champion which deviates in coloration and size from its more common form. The champion's coloration denotes which peculiar behaviors and traits it will exhibit. Champions will generally drop a pickup (coinciding with the color of the champion) when killed on normal difficulty. However, in hard mode, fewer champions will drop pickups on death. All champions will deal contact damage, regardless of what monster they are (e.g. a common Mulligan will not deal contact damage, but champion versions will). Some champions inflict full heart damage regardless of chapter. The likelihood of champions appearing is increased by unlocking the Everything Is Terrible! achievement, by carrying the Purple Heart trinket, by picking up the Champion Belt item, or by playing in hard mode. Champions are generally regarded as more dangerous than common monsters.

The identifying scheme for champion qualities is as follows:

精英类型

Appearance Effect Drop
Black Fades in and out of visibility, like a Null Red Chest
Solid White Invincible until other enemies are killed Eternal Heart
Transparent White Tears become spectral tears, and it can move past environmental obstacles (such as pits) that it otherwise couldn't when forced Golden Chest
Green Leaves green creep as it walks. Pill
Dark Teal Explodes when killed. Bomb
Gray Has 2/3 health, but deals double damage. Key
Orange Attacks cause you to drop coins (like Greed or a Keeper). Coin
Purple Pulls Isaac toward it, like a Gaping Maw. random Trinket
Red ×2.5 amount of HP. Heart
Dark Red Collapses into a flesh pile upon death and regenerates if not finished off (like a Globin). 1+1 Free Heart
Yellow Increased movement and shot speed. Battery
Light Blue Releases blood shots in 8 directions when killed. 1/2 heart
Dark Blue None. 3 Blue Flies
Pink Periodically shoots short-ranged blood shots, similar to Gushers. Nothing
DLC.png Pulsing Green Splits into two copies of itself upon death. 2 normal versions of itself
DLC.png Large Increased health, decreased speed. Larger and easier to hit. Deals two full hearts of damage. One makes you larger Pill
DLC.png Tiny Decreased health, increased speed. Smaller and more difficult to hit. One makes you small Pill
DLC.png Holy Has 1-2 eternal flies circling it. Spawns another fly upon death. Attack Fly
DLC.png Camouflage The enemy blends into the background and briefly becomes visible when damaged. Rune
DLC.png Pulsing Black Repels Isaac's shots when it pulses. Heart

Monster Variants

These uncommon variants may replace common enemies in a room.

Rebirth

Base Monster Possible Replacements
Mulligan.png Mulligoon.png or Mulliboom.png
Hopper.png Trite.png
Stone Grimace.png Vomit Grimace.png
Dople.png Evil Twin.png
Eye.png Bloodshot Eye (Monster).png
Leech (Monster).png Kamikaze Leech.png or Holy Leech.png
Maw.png Red Maw.png or Psychic Maw.png
Host.png Red Host.png
Vis.png Double Vis.png or Chubber.png
Boom Fly.png Red Boom Fly.png
Pooter.png Fat Fly.png
Pacer.png Gusher.png
Knight.png Selfless Knight.png
Clotty.png or Clot.png I.Blob.png
MemBrain.png Mama Guts.png
Gaper.png Frowning Gaper.png
Globin.png Gazing Globin.png
Baby.png Angelic Baby.png
Boil.png or Sack.png Gut.png
Sucker.png Spit.png

Afterbirth

Base Monster Possible Replacements
Gaper.png Flaming Gaper.png
Fatty.png Flaming Fatty.png
Hive.png Drowned Hive.png
Charger.png Drowned Charger.png
Squirt.png Dank Squirt.png
Death's Head.png Dank Death's Head.png or Flesh Death's Head.png
Globin.png Dank Globin.png
Guts.png Scarred Guts.png
Para-Bite.png Scarred Para-Bite.png
Double Vis.png Scarred Double Vis.png
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